[HTML][HTML] Hematopoietic progenitor kinase 1 down-regulates the oncogenic receptor tyrosine kinase AXL in pancreatic cancer
X Song, H Akasaka, H Wang… - Journal of Biological …, 2020 - ASBMB
The oncogenic receptor tyrosine kinase AXL is overexpressed in cancer and plays an
important role in carcinomas of multiple organs. However, the mechanisms of AXL
overexpression in cancer remain unclear. In this study, using HEK293T, Panc-1, and Panc-
28 cells and samples of human pancreatic intraepithelial neoplasia (PanIN), along with
several biochemical approaches and immunofluorescence microscopy analyses, we sought
to investigate the mechanisms that regulate AXL over-expression in pancreatic ductal …
important role in carcinomas of multiple organs. However, the mechanisms of AXL
overexpression in cancer remain unclear. In this study, using HEK293T, Panc-1, and Panc-
28 cells and samples of human pancreatic intraepithelial neoplasia (PanIN), along with
several biochemical approaches and immunofluorescence microscopy analyses, we sought
to investigate the mechanisms that regulate AXL over-expression in pancreatic ductal …
