Development of gonadotropin-releasing hormone-1 neurons
S Wray - Frontiers in neuroendocrinology, 2002 - Elsevier
Gonadotropin releasing hormone-1 (GnRH-1) neurons, critical for reproduction, are derived
from the nasal placode and migrate into the brain during prenatal development. Once within
the brain, GnRH-1 cells become integral components of the CNS–pituitary–gonadal axis,
essential for reproductive maturation and maintenance of reproductive function in adults.
This review focuses on the lineage and development of the GnRH-1 neuroendocrine
system. Although the migration of these cells from nose to brain has been well documented …
from the nasal placode and migrate into the brain during prenatal development. Once within
the brain, GnRH-1 cells become integral components of the CNS–pituitary–gonadal axis,
essential for reproductive maturation and maintenance of reproductive function in adults.
This review focuses on the lineage and development of the GnRH-1 neuroendocrine
system. Although the migration of these cells from nose to brain has been well documented …
