The natural history of acute histologic rejection without biochemical graft dysfunction in orthotopic liver transplantation: a systematic review

AS Bartlett, R Ramadas, S Furness, E Gane… - Liver …, 2002 - Elsevier
Protocol biopsy results in the first few weeks after liver transplantation sometimes display
histologic features of acute cellular rejection (ACR), even in the absence of significant
clinical or biochemical dysfunction. At present there is no clear consensus about the need to
treat such cases with adjuvant immunosuppression. This systematic review describes, from
the available evidence, the natural history of untreated histologic ACR in the absence of
biochemical graft dysfunction. An electronic search of the Medline, Embase, and Cochrane …