[HTML][HTML] Re-examination of the lymphocytotoxic crossmatch in liver transplantation: can C4d stains help in monitoring?
J Lunz, KM Ruppert, MM Cajaiba, K Isse… - American Journal of …, 2012 - Elsevier
C4d-assisted recognition of antibody-mediated rejection (AMR) in formalin-fixed paraffin-
embedded tissues (FFPE) from donor-specific antibody-positive (DSA+) renal allograft
recipients prompted study of DSA+ liver allograft recipients as measured by lymphocytotoxic
crossmatch (XM) and/or Luminex. XM results did not influence patient or allograft survival, or
cellular rejection rates, but XM+ recipients received significantly more prophylactic steroids.
Endothelial C4d staining strongly correlates with XM+ (< 3 weeks posttransplantation) and …
embedded tissues (FFPE) from donor-specific antibody-positive (DSA+) renal allograft
recipients prompted study of DSA+ liver allograft recipients as measured by lymphocytotoxic
crossmatch (XM) and/or Luminex. XM results did not influence patient or allograft survival, or
cellular rejection rates, but XM+ recipients received significantly more prophylactic steroids.
Endothelial C4d staining strongly correlates with XM+ (< 3 weeks posttransplantation) and …