The mobilization of antigen-presenting dendritic cells (DCs) from peripheral tissues to
draining lymph nodes drives the initiation of adaptive immune responses. Recent advances
have been made in understanding how and where DCs enter the lymphatic vasculature and
what mechanisms control this process. In this chapter, we highlight these advances.
Delineating DC–lymphatic vessel interactions is critical for our fundamental understanding
of DC trafficking in states of health and disease and for efforts to manipulate DC mobilization …